• REDUCED CUTANEOUS MICROVASCULAR REACTIVITY IN DIABETES MELLITUS TYPE 2

    Z. Stoyneva
    Clinic of Occupational Diseases, University Hospital St. Ivan Rilsky, Medical University – Sofia, Bulgaria

    Objective: to investigate skin vasomotor reflex responses in type 2 diabetic patients using laser Doppler flowmeter (LDF).

    Material and Methods: Skin blood flow was measured at the first tiptoe of each foot of 89 patients with type 2 diabetes mellitus and of 44 healthy controls during: local heating to 440C; venoarteriolar test by measuring sympathetic axon-reflex microcirculatory responses to foot lowering; reactive hyperemia test using laser Doppler flowmeter Periflux4001.

  • ASSESSMENT OF MICROVASCULAR CHANGES IN HAND-ARM VIBRATION SYNDROME

    Z. Stoyneva
    Clinic of Occupational Diseases, University Hospital St. Ivan Rilsky, Medical University – Sofia, Bulgaria

    Objective: To assess microvascular morphological and functional changes in patients with hand-arm vibration syndrome (HAVS).

    Material and Methods: Thirty HAVS patients and 30 healthy controls were included. After acclimatization, all subjects underwent nailfold capillaroscopy (NFC) and infrared thermography followed by laser Doppler flowmetry measurement. NFC was performed with a microscope under 10× to 20× magnification in the eponychium of the fingers. Skin blood flow of the volar part of the fingertips was measured using laser Doppler flowmeter Periflux4001 at baseline and by lowering the arm from heart level hanging to test skin venoarteriolar microcirculatory responces.