• CEREBRAL VASCULAR REACTIVITY IN PATIENTS WITH DIABETES MELLITUS TYPE 2

    I. Velcheva 1, P. Damianov 1, K. Stambolieva 2
    1 University Hospital of Neurology and Psychiatry, Medical University – Sofia,
    2 Institute of Neurobiology, Bulgarian Academy of Sciences – Sofia, Bulgaria

    Objective: To study the changes of the cerebral vascular reactivity after different stimuli in patients with diabetes mellitus type 2.

    Material and Methods: Twenty patients with diabetes mellitus type 2 (age range 45-67years) and 10 presumed healthy age and sex matched controls were included in the study. Simultaneous transcranial Doppler, blood pressure and heart rate monitoring was performed at rest and after cold stress, deep breathing and head-up tilt. The systolic (SBP), diastolic (DBP) and mean blood pressure (MBP) were measured and the blood flow velocity (BFV) parameters of the middle cerebral artery (MCA) were recorded. Comparison of the effects of the different stimuli on the blood pressure and BFV was performed.