F. Tranquart 1, B. Petit 1,2, E. Bihel 1, Y. Bohren 1, F. Yan 1, E. Allemann 2, M. Arditi 1, J. M. Hyvelin 1
1 BRACCO SUISSE SA – Plan Les Ouates, Switzerland, 
2 School of Pharmaceutical Sciences, University of Geneva, University of Lausanne – Geneva, Switzerland

Rapid restoration of vascular flow is the primary goal of acute stroke treatment, while improvement in patient’s outcome is the ultimate benefit of such treatments. Among different treatment schemes, sonothrombolysis has been used in in vitro tests, in preclinical trials and to a lesser extent in clinical trials, even though the exact underlying mechanism has not been fully clarified.