Y. Kim 1, J-H. Lee 2, W-G. Seo 3, S-U. Kwon 4
1 Ewha Womans University Mokdong Hospital – Seoul, Korea,
2 NHIS Ilsan Hospital – Ilsan, Korea,
3 Korea University Guro Hospital – Seoul, Korea,
4 Ulsan University Asan Medical Center – Seoul, Korea

Objective: It is reported that the occurrence of cerebral hemorrhage tends to increase in cases of accompanying lacunar infarction which occurs more frequently in Asians than in Westerners, or periventricular ischemic change which increasingly occurs with ageing. Accordingly, the point is that the occurrence of cerebral hemorrhage should be primarily considered in the treatment of cerebral infarction, along with the phenomenon of an ageing population both in Asian countries including Korea. Nevertheless, so far there has been no clinical research regarding secondary prevention of stroke, particularly considering the risk of occurrence of hemorrhage in cerebral infarction cases. However, according to a recent study, when phosphodiesterase inhibitors including cilostazol are used independently, or in combination with aspirin, secondary prevention can be improved without increasing the occurrence of hemorrhagic side effects.