Objective: To analyze all the possible risk factors for single and multiple of craniocervical artery dissection (CCAD).
Material and Methods: Data of 25 patients admitted to the Neurology Department, clinically presented with CCAD, during a two-year period were analyzed. Risk factors and 3-month outcome were assessed separately for single and multiple artery involvement. Descriptive statistics was used to present clinical characteristics, risk factors and other comorbidities from medical history, as well as clinical outcome. Intergroup comparison was performed.
Results: Multiple artery involvement accounted for 8/25 patients. Arterial hypertension was the most common risk factor for all patients. Migraine and thyroid abnormalities (hyperthyreosis, remote thyroidectomy) were the most common abnormalities in the group of patients with multiple artery involvement. Hypertension and hyperlipidemia were the most common risk factor for carotid dissection. All patients had favorable outcome (mRS <3).
Discussion: Thyroid abnormalities, not previously reported, were common risk factors for multiple artery involvement in CCAD.

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