S. Andonova-Atanasova 1, F. Kirov 1, M. Petkova 1, P. Kirilova 1, E. Kalevska 1, V. Argirova 1, Zv. Zvetkov 1, M. Novakova 2, R. Georgiev 2, V. Georgieva 3
1 Department of Neurology, Second Clinic of Neurology,
2 Department of Radiology, 3Centre of Emergency, University Hospital St. Marina – Varna, Bulgaria

Objective: The aim of the present study is to describe the results and the problems in evaluation of the thrombolytic therapy for management of acute ischemic stroke in the Second clinic of Neurology with Intensive Neurology Care Unit .

Material and Methods: One hundred twenty two patients (mean age 68.3±7.2 years) with acute stroke, hospitalized in the period between 01.08.2009 and 31.05.2013 were studied. The following factors: time between onset of symptoms, NIH-stroke scale, Rankin score were recorded on the admission and three months after dehospitalisation. The relationship between the time of diagnosis of ischaemic stroke and the time of treatment was studied.

Results: The first thrombolysis in Varna was done in Second Clinic of Neurology on April 2007. Until December 2009 were implemented 20 thrombolyses. The problems of organisation and management are described. The main technical difficulties and findings in preparation were pointed out. From December 2009 to May 2013 significantly was decreased “door to niddle time” through the good management of stroke patients.

Discussion: Stroke is an emergency. The effective treatment of stroke already exists - thrombolytic therapy. For optimal treatment exists a therapeutic window. Thrombolysis lead to decrease of disability and mortality.

Key words: management of ischemic stroke, thrombolysis.

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